GWAS Pipeline
Accelerate genomic analysis, target discovery, and drug discovery by efficiently interrogating WES datasets at biobank scale with a proven Genome-wide Association Studies (GWAS) pipeline platform
Context
Streamlining GWAS Analysis for Deeper Insights into Complex Traits
With several disorders finding their genetic causes through genome-wide association studies (GWAS), scientists are closer than ever to understanding the link between genes and complex diseases. However, despite the progress made with GWAS, navigating the analysis itself presents several bottlenecks such as case-control imbalance, sheer volume of data, statistical noise, population stratification bias, and a lack of user-friendly interfaces. Current GWAS tools come with limitations as they are built for specific data formats or require extensive technical knowledge.
Aganitha’s GWAS capabilities can help Biopharma R&D overcome these challenges and accelerate drug discovery. We offer two key solutions:
Aganitha’s GWAS capabilities can help Biopharma R&D overcome these challenges and accelerate drug discovery. We offer two key solutions:
- Customizable GWAS Pipelines: We help you build a robust extensible pipeline for all your GWAS analysis needs. Our scientific and technical team will work with you to build a customized platform and pipeline for your GWAS analysis.
- Actionable Insights from Data: We provide you with a dedicated scientific team to analyze WGS/WES data at a biobank scale and provide actionable insights such as identifying targets, and identifying disease causing variants, etc.
Our Solution
Accelerate your disease studies using our GWAS platform for genomic analysis
The following our some key features of our pipeline:
- Available on-demand: Enabling you to access our pipeline that is powered by the Infrastructure as Code approach, supporting both in-house HPC as well as all Cloud-based clusters
- Cost-effective: Minimizing your expenses by avoiding dependence on expensive proprietary big data stacks such as UK Biobank and related services.
- Comprehensive: Spanning all activities from data ingestion and QC to cohort selection, regression, and visualization. This puts you in complete control of your analysis, all within a secure environment.
- Interactive Empowering your scientists to participate actively in the analysis. They can inspect and apply relevant sample and variant QCs, meticulously design study cohorts, and gain deeper insights from their data.
- Offers seamless expertise: Ensuring comprehensive support throughout your analysis process by leveraging Aganitha’s extensive genomics and technology expertise. Our team becomes an extension of yours, assisting you towards successful outcomes.
- Streamlined Resources Streamlining your analysis workflows by providing ready access to essential reference datasets, annotation, and visualization tools.
Challenges addressed
At Aganitha, we recognize and understand the complexities that can hinder your progress in GWAS research. We take these challenges head-on and empower your research success. Some of these challenges include: